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A general description is here.
The script editor in Rgui now works also on systems using UTF-8 as the native encoding. Users of the script editor have to convert their scripts with non-ASCII characters to UTF-8 before reading them in R 4.2.1 or newer (on recent Windows where UTF-8 is used). This fixes a regression in R 4.2.0, which prevented some operations with scripts when they contained non-ASCII characters.
Text injection from external applications via ‘SendInput’ now works in GraphApp Unicode windows, fixing a regression in R 4.2.0 for Rgui users of systems where R 4.1 used a single-byte locale but R 4.2.0 uses UTF-8.